Urethral stricture: Investigation of demographic characteristics in two tertiary hospitals in Isfahan/Iran

Hamid Mazdak, AbdoulKarim Khorrami, Zahra Tolou-Ghamari


According to previous publication, urethral stricture is a common pathology with dissimilar etiologic features in diverse age groups and societies. The aim of this study was to investigate demographic characteristics in two tertiary hospitals in Isfahan/Iran. All patients with urethral strictures were obtained from 2008 to 2018 from urology wards located at the two tertiary hospitals in Isfahan/Iran. According to ICD-10, demographic and clinical information were recorded in Excel and analyzed by SPSS. Age, as a continuous variable, was expressed as mean ± standard deviation (SD). A p value of <0.05 was considered as significant. For a period of 10 years there were a total of 1792 patients comprised of 433 females and 1359 males with urethral strictures. The mean ± SD of age was 41.9 ±24.5 years old. With a between age of 30 to 70 in 71% females showed disease at younger duration of life (p<0.001). Urethral strictures was occurred in 30% under the age of 10 years old. The pattern of attendance for most patients was once and in ranged from 2 to 5. Intermediate time for those with the pattern of recurrence ranged from 8 to 3074 days after surgery. Urethral strictures categorized as an undertreated disease both nationally and internationally. In this study for over a period of ten years, around 1792 patients’ visited two tertiary hospitals in Isfahan/Iran due to urethral strictures disease. Therefore in order to reduce the severity of disease and associated costs, identifying risk factors for occurrence or progression in addition to pharmacotherapy approach recommended to be advantageous.


Urethra, Strictures, Urethrotomy, Demographic, Isfahan

Full Text:



Almannie RM, Alkhamis WH, Alshabibi AI. Management of urethral strictures: A nationwide survey of urologists in the Kingdom of Saudi Arabia. Urol Ann 10: 363-368, 2018.

Alwaal A, Blaschko SD, McAninch JW, Breyer BN. Epidemiology of urethral strictures. TranslAndrol Urol 3:209-213, 2014.

Santucci RA, Joyce GF, Wise M. Male urethral stricture disease.J Urol 177:1667-1674, 2007.

Palminteri E, Berdondini E, Verze P, et al. Contemporary urethral stricture characteristics in the developed world.Urology 81:191-196, 2013.

Stein DM, Thum DJ, Barbagli G, et al. A geographic analysis of male urethral stricture aetiology and location. BJU Int 112:830-834, 2013.

Mazdak H, Izadpanahi MH, Ghalamkari A, Kabiri M, Khorrami MH, Nouri-Mahdavi K, Alizadeh F, Zargham M, Tadayyon F, Mohammadi A, Yazdani M. Internal urethrotomy and intraurethral submucosal injection of triamcinolone in short bulbar urethral strictures. Int Urol Nephrol 42:565-568, 2010.

Mazdak H, Meshki I, Ghassami F. Effect of mitomycin C on anterior urethral stricture recurrence after internal urethrotomy. Eur Urol 51:1089-1092, 2007.

WA De S. General considerations on and the role of internal urethrotomy in the treatment of urethral stricture. Ann Urol (Paris) 7:203-208, 1993

Santucci RA, Joyce GF, Wise M. Male urethral stricture disease. J Urol 177:1667-1674, 2007.

Frankel JK, Murphy GP. International volunteerism and urethral stricture disease: a review. Transl Androl Urol 7:659-665, 2018.

Mazdak H, Tolou_Ghamari Z. Preliminary study of prevalence for bladder cancer in Isfahan Province, Iran.Arab J Urol 16:206-210, 2018.

Mazdak H, Tolou_Ghamari Z. Frequency of genito-urinary tract disorders in a tertiary hospital in Isfahan, Iran. Am J Exp Clin Res 5:258-262, 2018.

Campain NJ, MacDonagh RP, Mteta KA, et al. Global surgery - how much of the burden is urological? BJU Int 116:314-316, 2015.

Fuller TW, Pekala K, Theisen KM, Tapper A, Burks F, Rusilko PJ. Prevalence and surgical management of concurrent adult acquired buried penis and urethral stricture disease. World J Urol Oct 8, 2018.

Carr L.K., Webster G.D. Bladder outlet obstruction in women. Urol Clin North Am 23:385-391, 1996.

Kuo H.C. Video urodynamic characteristics and lower urinary tract symptoms of female bladder outlet obstruction. Urology 66:1005-1009, 2005.

Gormley E.A. Vaginal flap urethroplasty for female urethral stricture disease. Neurourol Urodyn 29(Suppl 1):S42–S45, 2010.

Simonato A., Varca V., Esposito M., Carmignani G. Vaginal flap urethroplasty for wide female stricture disease. J Urol 184:1381-1385, 2010.

Aldamanhori R, Inman R.The treatment of complex female urethral pathology. Asian J Urol 5:160-163, 2018.

Akyüz M, Tokuç E, Özsoy E, Koca O, Kanberoğlu H, Öztürk M, Topaktaş R.Characteristics of the urethroplasty and our approach-Experience in patients with urethral stricture. Turk J Urol Nov 21, 2018.

Méndez Rubio S, Salinas Casado J, Vírseda Chamorro M, Gutiérrez Martín P, Esteban Fuertes M, Moreno Sierra J.Other radiological lesions of the Lower Urinary Tract in patients after isolated pelvic radiotherapy and combined with surgery. Arch Esp Urol 69:59-66, 2016.


  • There are currently no refbacks.