A rare cause of anemia due to upper gastrointestinal bleeding: Cameron lesion

Ismet Özaydın, Sami Doğan, Arif Aslaner, Mehmet Yaşar, Metin Aydın

Abstract


Asymptomatic large hiatal hernias may lead to iron deficiency anemia due to occult and massive bleeding from linear gastric erosions or ulcers on the mucosal folds at the level of the diaphragm called the Cameron lesions. The diagnosis is usually made during upper gastrointestinal system endoscopies. Current therapy includes the medication with proton pump inhibitors in combination with oral iron supplements and in some cases surgical reconstruction of hiatal hernia with fundoplication. We present a case of a 78-year-old woman who was admitted to the outpatient clinic with the diagnosis of iron deficiency anemia without signs of acute gastrointestinal bleeding. She was treated with medication and her follow-up gastroscopy showed a total cure. She is asymptomatic for two years after treatment with proton pump inhibitors and iron supplements. Cameron lesions should be kept in mind as an unusual cause of iron deficiency anemia due to gastrointestinal bleeding.

 


Keywords


Cameron lesion, anemia, hiatal hernia

Full Text:

PDF

References


Johnson DA, Ruffin WK: Hiatal hernia. Gastrointest Endosc Clin N Am 6:641-667, 1996.

Cameron AJ, Higgins, JA. Linear Gastric Erosion: A lesion associated with large diaphragmatic hernia and chronic blood loss anemia. Gastroenterology 91:338-342, 1986.

Sleisenger & Fordtran’s Gastrointestinal and Liver Disease, 7th ed. Philadelphia, Saunders, 2002.

Cameron AJ. Incidence of iron deficiency anemia in patients with large diaphragmatic hernia: A controlled study. Mayo Clin Proc 51:U767-769, 1976.

Maganty K, Smith R L. Cameron lesions: Unusual cause of gastrointestinal bleeding and anemia. Digestion 77:214-217, 2008.

Bock AV, Dulin JW, Brooke PA. Diaphragmatic hernia and secondary anemia: 10 cases. New Engl J Med 209:615, 1933.

Panzuto F, Di Giulio E, Capurso G, et al. Large hiatal hernia in patients with iron deficiency anemia: A prospective study on prevalence and treatment. Aliment Pharmacol Ther 19:663-670, 2004.

Moskovitz M, Fadden R, Min T, Jansma D, Gavaler J. Large hiatal hernias, anemia, and linear gastric erosion: Studies of etiology and medical therapy. Am J Gastroenterol 87:622-626, 1992.

Nguyen N, Tam W, Kimber R, Roberts-Thomson IC. Gastrointestinal: Cameron’s erosions. J Gastroenterol Hepatol 17:343, 2002.

Weston AP. Hiatal hernia with Cameron ulcers and erosions. Gastrointest Endosc Clin N Am 6:671-679, 1996.

Colin W, Windsor O, Leigh Collis J. Anemia and hiatus hernia: Experience in 450 patients. Thorax 22:73-78, 1967.

Trastek VF, Allen MS, Deschamps C, et al. Diaphragmatic hernia and associated anemia: Response to surgical treatment. J Thorac Cardiovasc Surg 112:1340-1344; discussion 1344-1345, 1996.


Refbacks

  • There are currently no refbacks.